Denver Broncos open as underdogs at home vs. Tampa Bay Buccaneers

San Francisco 49ers road favorites vs. New York Giants in Week 3

Tennessee Titans open as road favorites vs. Minnesota Vikings in Week 3

Buffalo Bills open as slight favorites in Week 3 game vs. Los Angeles Rams

Indianapolis Colts are Week 3's biggest betting favorites against New York Jets

Undefeated Chicago Bears early Week 3 underdogs against Atlanta Falcons

Cleveland Browns big home favorites against Washington Football Team in Week 3

Houston Astros at Seattle Mariners odds, picks and best bets

Texas Rangers at Los Angeles Angels odds, picks and best bets

Arizona Cardinals open as favorites in Week 3 vs. Detroit Lions

Dallas Stars vs. Tampa Bay Lightning Stanley Cup Final odds, picks and best bets